Please do not talk about different aspects of the immune system and bring it together, that is not the style I am looking for. I would like to introduce the caspase 8 function its importance and end introductory paragraph with hypothesis about CEDS. The body paragraph should explore function of casp8 and exploring the importance of its function in the immune system. every function should be explored in more detail how exactly what pathways and which proteins are involved. what pathways and systems does the caspase regulate and play an important role in. Also when casp8 gene mutation happens what else is affected with it. The last body paragraph should talk about diagnosis briefly, living with it and treatment. The last paragraph can include any current advanced treatment and/or clinical trials. Finally the body paragraph can summarize a little and bring everything beautifully together. The whole research paper should convey deep understanding of the immune system.